The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2009
Filed:
Sep. 29, 2003
Mark Mccormick, Madison, WI (US);
Klaus-peter Stengele, Pleiskirchen, DE;
Gary Barrett, Madison, WI (US);
Roland Green, Madison, WI (US);
Mark McCormick, Madison, WI (US);
Klaus-Peter Stengele, Pleiskirchen, DE;
Gary Barrett, Madison, WI (US);
Roland Green, Madison, WI (US);
Roche Nimblegen, Inc., Madison, WI (US);
Abstract
The present invention is a microarray having a plurality of subarrays with a hydrophobic barrier that defines each subarray of the microarray, and a method for preparing such a microarray. The hydrophobic barrier is prepared using a microarray synthesis instrument, where NPPOC photoprotected and other hydrophobic group-bearing phosphoramidites are coupled to the microarray using light from a digital micromirror to direct formation of the hydrophobic barrier. The method utilizes hydrophobicity, a well-established property, of conventional phosphoramidite protecting groups for an entirely new application, the synthesis of hydrophobic barriers on microarrays.