The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2009

Filed:

Apr. 11, 2003
Applicants:

Robert J. Hariri, Florham Park, NJ (US);

David I. Stirling, Warren, NJ (US);

Laure A. Moutouh-de Parseval, San Diego, CA (US);

Kyle W. H. Chan, San Diego, CA (US);

Inventors:

Robert J. Hariri, Florham Park, NJ (US);

David I. Stirling, Warren, NJ (US);

Laure A. Moutouh-De Parseval, San Diego, CA (US);

Kyle W. H. Chan, San Diego, CA (US);

Assignee:

Anthrogenesis Corporation, Warren, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to methods of modulating mammalian stem cell and progenitor cell differentiation. The methods of the invention can be employed to regulate and control the differentiation and maturation of mammalian, particularly human stem cells along specific cell and tissue lineages. The methods of the invention relate to the use of certain small organic molecules to modulate the differentiation of stem or progenitor cell populations along specific cell and tissue lineages, and in particular, to the differentiation of embryonic-like stem cells originating from a postpartum placenta or for the differentiation of early progenitor cells to a granulocytic lineage. Finally, the invention relates to the use of such differentiated stem or progenitor cells in transplantation and other medical treatments.


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