The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2009

Filed:

Nov. 17, 2000
Applicants:

Roger Briesewitz, Mountain View, CA (US);

Gerald R. Crabtree, Woodside, CA (US);

Thomas J. Wandless, Stanford, CA (US);

Inventors:

Roger Briesewitz, Mountain View, CA (US);

Gerald R. Crabtree, Woodside, CA (US);

Thomas J. Wandless, Stanford, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 7/06 (2006.01); C07K 5/10 (2006.01); C07K 5/00 (2006.01); C12N 9/90 (2006.01);
U.S. Cl.
CPC ...
Abstract

Targeted bifunctional molecules and methods for their use are provided. The subject targeted bifunctional molecules are conjugates of a drug moiety and a targeting moiety, where these two moieties are optionally joined by a linking group. The bifunctional molecules are further characterized in that they exhibit a modulated biodistribution upon administration to a host as compared to a free drug control. The subject targeted bifunctional molecules find use in a variety of therapeutic applications.


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