The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2009
Filed:
Sep. 04, 2003
Dennis Ausiello, Wellesley Hill, MA (US);
John T. Santini, Jr., North Chelmsford, MA (US);
Stephen J. Herman, Andover, MA (US);
James H. Prescott, Cambridge, MA (US);
Scott A. Uhland, Roslindale, MA (US);
John M. Maloney, Cambridge, MA (US);
Benjamin F. Polito, Lebanon, NH (US);
Dennis Ausiello, Wellesley Hill, MA (US);
John T. Santini, Jr., North Chelmsford, MA (US);
Stephen J. Herman, Andover, MA (US);
James H. Prescott, Cambridge, MA (US);
Scott A. Uhland, Roslindale, MA (US);
John M. Maloney, Cambridge, MA (US);
Benjamin F. Polito, Lebanon, NH (US);
MicroCHIPS, Inc., Bedford, MA (US);
Abstract
Method and devices are provided for extended and controlled delivery of parathyroid hormone to a patient. The method includes implanting a medical device into the patient, the medical device comprising a substrate, a plurality of reservoirs in the substrate, a release system contained in each of the reservoirs, wherein the release system comprises parathyroid hormone; and controllably releasing a pharmaceutically effective amount of the parathyroid hormone from the reservoirs. The parathyroid hormone can be released intermittently, such as once daily over an extended period (e.g., two months, ten months, or more.). The device can further include reservoirs containing a bone resorption inhibitor or other drug for release. The devices are useful in delivering PTH for the treatment and prevention of bone loss, such as associated with osteoporosis.