The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2009
Filed:
May. 09, 2005
Mark S. Cushman, West Lafayette, IN (US);
Andrew E. Morrell, Bristol, TN (US);
Yves G. Pommier, Bethesda, MD (US);
Mark S. Cushman, West Lafayette, IN (US);
Andrew E. Morrell, Bristol, TN (US);
Yves G. Pommier, Bethesda, MD (US);
Purdue Research Foundation, West Lafayette, IN (US);
The United States of America as represented by the Department of Health and Human Services, Washington, DC (US);
Abstract
Indenoisoquinolines and dihydroindenoisoquinolines are described. In particular, such compounds possessing one or more electron withdrawing substituents are described. The in vitro anticancer activities of these molecules tested in the National Cancer Institute's screen of 55 cell lines is described. The compounds tested for topoisomerase I (top1) inhibition is described.