The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2009

Filed:

Jun. 28, 1994
Applicants:

Christine L. Brakel, Brightwaters, NY (US);

James G. Wetmur, Scarsdale, NY (US);

Robin S. Quartin, Bedminster, NJ (US);

Inventors:

Christine L. Brakel, Brightwaters, NY (US);

James G. Wetmur, Scarsdale, NY (US);

Robin S. Quartin, Bedminster, NJ (US);

Assignee:

Enzo Life Sciences, Inc., Farmingdale, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12P 21/06 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed is a nuclease resistant nucleotide compound capable of hybridizing with a complementary RNA in a manner which inhibits the function thereof, which modified nucleotide compound includes at least one component selected from the group consisting of MNM, B(N)M and M(N)B wherein N is a phosphodiester-linked modified 2'-deoxynucleoside moiety; M is a moiety that confers endonuclease resistance on said component and that contains at least one modified or unmodified nucleic acid base; B is a moiety that confers exonuclease resistance to the terminus to which it is attached; and x is an integer of at least 2.


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