The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2009
Filed:
Mar. 18, 2005
Applicants:
Fred E. Cohen, San Francisco, CA (US);
Xiaohui Du, Los Angeles, CA (US);
Chun Guo, Shenyang, CN;
James H. Mckerrow, San Francisco, CA (US);
Inventors:
Fred E. Cohen, San Francisco, CA (US);
Xiaohui Du, Los Angeles, CA (US);
Chun Guo, Shenyang, CN;
James H. McKerrow, San Francisco, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/38 (2006.01); C07D 333/12 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to thio semicarbazone and semicarbazone inhibitors of cysteine proteases and methods of using such compounds to prevent and treat protozoan infections such as trypanosomiasis, malaria and leishmaniasis. The compounds also find use in inhibiting cysteine proteases associated with carcinogenesis, including cathepsins B and L.