The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2009

Filed:

Feb. 12, 2004
Applicants:

Nathan A. Chubb, Deal, GB;

Douglas J. Critcher, Deal, GB;

James J. Eshelby, Broadstairs, GB;

Graham Lunn, Canterbury, GB;

Andrew J. Rudge, Sandwich, GB;

Nigel D. Walshe, Deal, GB;

Paul H Wiedenau, Deal, GB;

David H. Williams, Canterbury, GB;

Inventors:

Nathan A. Chubb, Deal, GB;

Douglas J. Critcher, Deal, GB;

James J. Eshelby, Broadstairs, GB;

Graham Lunn, Canterbury, GB;

Andrew J. Rudge, Sandwich, GB;

Nigel D. Walshe, Deal, GB;

Paul H Wiedenau, Deal, GB;

David H. Williams, Canterbury, GB;

Assignee:

Pfizer Inc., New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/04 (2006.01); A61K 31/5365 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to novel terpene alkaloids and their use as antiparasitic agents. The present invention also relates to an antiparasitic agent which comprises a terpene alkaloid compound of this invention as an effective ingredient in an antiparasitic formulation. More particularly, the present invention relates to derivatives of the terpene alkaloid (1S,2R,4aS,5R,8R,8aR)-2-(acetyloxy)-8a-hydroxy-3,8-dimethyl-5-(1-methylethenyl)-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl (2S,3aR,9bR)-6-chloro-9b-hydroxy-5-methyl-1,2,3,3a,5,9b-hexahydropyrrolo[2,3-c][2,1]benzoxazine-2-carboxylate. Pharmaceutical compositions comprising the same are also disclosed.


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