The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2009
Filed:
Apr. 13, 2006
Daniela Tornese Buonamassa, Siena, IT;
Catherine E. Greer, Oakland, CA (US);
Cesira L. Galeotti, Montegriggioni, IT;
Giuliano Bensi, Florence, IT;
Roberto Petracca, Siena, IT;
Daniela Tornese Buonamassa, Siena, IT;
Catherine E. Greer, Oakland, CA (US);
Cesira L. Galeotti, Montegriggioni, IT;
Giuliano Bensi, Florence, IT;
Roberto Petracca, Siena, IT;
Novartis Vaccines and Diagnostics, Inc., Emeryville, CA (US);
Abstract
Mosaic VLPs of viral capsid proteins from different virus types are described, as are methods of making the same. Specifically, a diploid yeast strain that coexpresses the L1 and L2 capsid proteins of both HPV-6 and HPV-16 as mosaic VLPs is described. The mosaic VLPs induced the production of conformational antibodies against both L1 proteins upon administration to mice.