The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 17, 2009

Filed:

Aug. 08, 2002
Applicants:

Kousuke Tani, Mishima-gun, JP;

Masaki Asada, Mishima-gun, JP;

Kaoru Kobayashi, Mishima-gun, JP;

Masami Narita, Mishima-gun, JP;

Mikio Ogawa, Mishima-gun, JP;

Inventors:

Kousuke Tani, Mishima-gun, JP;

Masaki Asada, Mishima-gun, JP;

Kaoru Kobayashi, Mishima-gun, JP;

Masami Narita, Mishima-gun, JP;

Mikio Ogawa, Mishima-gun, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/195 (2006.01); C07C 229/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

A carboxylic acid derivative of formula (I): wherein Ris —COOH, —COOR, etc.; A is a single bond, alkylene, etc.; Ris alkyl, alkoxy, etc.; B is a carbocyclic ring or a heterocyclic ring; Q is alkylnene-Cyc2, etc.; D is a linking chain; and Ris alkyl, a carbocyclic ring or a heterocyclic ring, or a non-toxic salt thereof. The compound of formula (I) binds to PGEreceptor, especially subtypes EPand/or EPand show the antagonizing activity, are useful for the prevention and/or treatment of diseases induced pain, itch, urticaria, allergy, urinary frequency, urinary disturbance, Alzheimer's disease, cancer, dysmenorrhea, endometriosis, etc.


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