The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2009
Filed:
Apr. 26, 2005
Lawrence J. Marnett, Nashville, TN (US);
Jeffery J. Prusakiewicz, Nashville, TN (US);
Andrew S. Felts, Nashville, TN (US);
Chuan Ji, Nashville, TN (US);
Lawrence J. Marnett, Nashville, TN (US);
Jeffery J. Prusakiewicz, Nashville, TN (US);
Andrew S. Felts, Nashville, TN (US);
Chuan Ji, Nashville, TN (US);
Vanderbilt University, Nashville, TN (US);
Abstract
The presently disclosed subject matter provides derivatives of non-steroidal anti-inflammatory drugs (NSAIDs) that are characterized by substantially reduced cyclooxygenase inhibiting activity, yet retain the ability to interact with and modulate the activities of other polypeptides such as the class of peroxisome proliferators-activated receptors (PPARs) and γ-secretase. Also provided are methods of using the derivatives to treat pathological disorders.