The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 17, 2009

Filed:

Dec. 17, 2003
Applicants:

Margaretha Bakker, Seeheim-Jugenheim, DE;

Wilfried Hornberger, Neustadt, DE;

Andreas Kling, Mannheim, DE;

Udo Lange, Mannheim, DE;

Helmut Mack, Ludwigshafen, DE;

Achim Moeller, Grundstadt, DE;

Reinhold Mueller, Schifferstadt, DE;

Kurt Schellhaas, Ludwigshafen, DE;

Martin Schmidt, Bensheim, DE;

Gerd Steiner, Kircheim, DE;

Karsten Wicke, Altrip, DE;

Inventors:

Margaretha Bakker, Seeheim-Jugenheim, DE;

Wilfried Hornberger, Neustadt, DE;

Andreas Kling, Mannheim, DE;

Udo Lange, Mannheim, DE;

Helmut Mack, Ludwigshafen, DE;

Achim Moeller, Grundstadt, DE;

Reinhold Mueller, Schifferstadt, DE;

Kurt Schellhaas, Ludwigshafen, DE;

Martin Schmidt, Bensheim, DE;

Gerd Steiner, Kircheim, DE;

Karsten Wicke, Altrip, DE;

Assignee:

Abbott GmbH & Co. KG, Wiesbaden, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/54 (2006.01); A61K 31/505 (2006.01); C07D 239/00 (2006.01); C07D 471/00 (2006.01); C07D 487/00 (2006.01); C07D 491/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

3-Substituted 3,4-dihydrothieno[2,3-d]pyrimidin-4-one derivatives, production and use thereof. The invention relates to 3,4-dihydrothieno[2,3-d]pyrimidin-4-one derivatives which are substituted in position 3 by 5-membered heteroaryl which may be fused to an aryl or heteroaryl radical, where the heteroaryl and, if appropriate, the fused aryl or heteroaryl radical may have 1, 2 or 3 substituents selected independently of one another from C-alkyl, C-alkoxy, C-alkylthio, halogen, CN, halo-C-alkyl, halo-C-alkoxy, hydroxy, —NH, —N(R6), —NH(R6), aryl, aryloxy, aralkyl, aralkyloxy and heteroaryl, where the substituents aryl, aryloxy, aralkyl, aralkyloxy and heteroaryl may have 1, 2 or 3 substituents selected independently of one another from C-alkyl, C-alkoxy, C-alkylthio, halogen, CN, halo-C-alkyl, halo-C-alkoxy, hydroxy, —NH, —N(R6)and —NH(R6). The preparation and use of these derivatives, especially for therapeutic purposes, e.g. for the treatment of depressions, are likewise described.


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