The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2009
Filed:
Mar. 01, 2004
Abraham Bout, Moerkapelle, NL;
Guus Hateboer, Heemstede, NL;
Karina Cornelia Verhulst, Leiden, NL;
Alphonsus Gerardus Uytdehaag, Debilt, NL;
Govert Johan Schouten, Leiderdorp, NL;
Abraham Bout, Moerkapelle, NL;
Guus Hateboer, Heemstede, NL;
Karina Cornelia Verhulst, Leiden, NL;
Alphonsus Gerardus Uytdehaag, Debilt, NL;
Govert Johan Schouten, Leiderdorp, NL;
Crucell Holland, B.V., Leiden, NL;
Abstract
Methods and compositions for the production of recombinant proteins in a eukaryotic cell line are disclosed. The methods and compositions are particularly useful for generating stable expression of recombinant proteins of interest that are modified post-translationally, for example, by glycosylation. Such proteins may have advantageous properties in comparison with their counterparts produced in non-human systems such as Chinese hamster ovary cells.