The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2009
Filed:
Jan. 17, 2005
Petronella C. Raemakers-franken, Budel, NL;
Petrus M. M. Nossin, Nederweert, NL;
Paul M. Brandts, Limbricht, NL;
Marcel G. Wubbolts, Sittard, NL;
Wijnand P. H. Peeters, Maasbree, NL;
Sandra Ernste, Landgraaf, NL;
Stefaan M. A. Wildeman DE, Kessel-Lo, BE;
Martin Schuermann, Juelich, DE;
Petronella C. Raemakers-Franken, Budel, NL;
Petrus M. M. Nossin, Nederweert, NL;
Paul M. Brandts, Limbricht, NL;
Marcel G. Wubbolts, Sittard, NL;
Wijnand P. H. Peeters, Maasbree, NL;
Sandra Ernste, Landgraaf, NL;
Stefaan M. A. Wildeman De, Kessel-Lo, BE;
Martin Schuermann, Juelich, DE;
DSM IP Assets B.V., Heerlen, NL;
Abstract
The invention relates to biochemical synthesis of 6-amino caproic acid from 6-aminohex-2-enoic acid compound or from 6-amino-2-hydroxyhexanoic acid, by treatment with an enzyme having α,β-enoate reductase activity towards molecules containing an α,β-enoate group and a primary amino group. The invention also relates to processes for obtaining suitable genetically engineered cells for being used in such biotransformation process, and to precursor fermentation of 6-amino caproic acid from intermediates leading to 6-amino caproic acid. Finally, the invention relates to certain novel biochemically produced compounds, namely 6-aminohex-2-enoic acid, 6-aminohexanoic acid, as well as to caprolactam produced therefrom and to nylon-6 and other derivatives produced from such biochemically produced compounds or caprolactam.