The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2009
Filed:
Nov. 04, 1999
Kevin R. MC Intosh, Ellicott City, MD (US);
Joseph D. Mosca, Ellicott City, MD (US);
Elena N. Klyushnenkova, Baltimore, MD (US);
Kevin R. Mc Intosh, Ellicott City, MD (US);
Joseph D. Mosca, Ellicott City, MD (US);
Elena N. Klyushnenkova, Baltimore, MD (US);
Osiris Therapeutics, Inc., Baltimore, MD (US);
Abstract
Disclosed is a method of inducing a reduced immune response to a transplant in a recipient by treating said recipient with an amount of fibroblasts or a supernatant from a fibroblast culture effective to reduce or inhibit host rejection of the transplant. The fibroblasts or a supernatant from a fibroblast culture can be administered before, at the same time as, or after the transplant. This method is effective in reducing an immune response to a transplant without compromising the immune response to other foreign antigens. Also disclosed is a method of inducing a reduced immune response against a host by foreign tissue, i.e., graft versus host disease.