The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7488491 B1

PDF
Full Text
Expired
Date of Patent:
Feb. 10, 2009

Filed:

Jul. 25, 2002
Applicants:

Moriya Tsuji, New York, NY (US);

Gloria Gonzalez-aseguinolaza, Baranain, ES;

Yasuhiko Koezuka, Gunma, JP;

Inventors:

Moriya Tsuji, New York, NY (US);

Gloria Gonzalez-Aseguinolaza, Baranain, ES;

Yasuhiko Koezuka, Gunma, JP;

Assignee:

New York University, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to methods and compositions for augmenting an immunogenicity of an antigen in a mammal, comprising administering said antigen together with an adjuvant composition that includes glycosylceramide, preferably α-galactosylceramide (α-GalCer). According to the present invention, the use of glycosylceramide as an adjuvant is attributed at least in part to the enhancement and/or extension of antigen-specific Th1-type responses, in particular, CD8+ T cell responses. The methods and compositions of the present invention can be useful for prophylaxis and treatment of various infectious and neoplastic diseases.


Find Patent Forward Citations

Tsuji, Moriya. (2009). Use of glycosylceramides as adjuvants for vaccines against infections and cancer (U.S. Patent No. 7488491). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7488491

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