The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 10, 2009

Filed:

Sep. 16, 1999
Applicants:

Naoto Miwa, Tokyo, JP;

Michihito Inagaki, Osaka, JP;

Hiroaki Eguchi, Hyogo, JP;

Masafumi Okumura, Shiga, JP;

Yoshio Inagaki, Kanagawa, JP;

Toru Harada, Kanagawa, JP;

Inventors:

Naoto Miwa, Tokyo, JP;

Michihito Inagaki, Osaka, JP;

Hiroaki Eguchi, Hyogo, JP;

Masafumi Okumura, Shiga, JP;

Yoshio Inagaki, Kanagawa, JP;

Toru Harada, Kanagawa, JP;

Assignees:

Schering AG, Berlin, DE;

Fuji Photo Film Co., Ltd., Kanagawa, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); C09B 23/08 (2006.01); G01N 33/53 (2006.01); C07D 291/00 (2006.01); C07D 231/06 (2006.01); C09K 11/06 (2006.01); A01N 43/38 (2006.01);
U.S. Cl.
CPC ...
Abstract

A near infrared fluorescent contrast agent comprising a compound having three or more sulfonic acid groups in a molecule, and a method of fluorescence imaging comprising introducing the near infrared fluorescent contrast agent of the present invention into a living body, exposing the body to an excitation light, and detecting near infrared fluorescence from the contrast agent. The near infrared fluorescent contrast agent of the present invention is excited by an excitation light and emits near infrared fluorescence. This infrared fluorescence is superior in transmission through biological tissues. Thus, detection of lesions in the deep part of a living body has been made possible. In addition, the inventive contrast agent is superior in water solubility and low toxic, and therefore, it can be used safely.


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