The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2009

Filed:

Jun. 19, 2002
Applicants:

Hans-michael Eggenweiler, Darmstadt, DE;

Michael Wolf, Darmstadt, DE;

Norbert Beier, Reinheim, DE;

Joachim Leibrock, Pfungstadt, DE;

Pierre Schelling, Mühltal, DE;

Michael Gassen, München, DE;

Thomas Ehring, Remscheid, DE;

Inventors:

Hans-Michael Eggenweiler, Darmstadt, DE;

Michael Wolf, Darmstadt, DE;

Norbert Beier, Reinheim, DE;

Joachim Leibrock, Pfungstadt, DE;

Pierre Schelling, Mühltal, DE;

Michael Gassen, München, DE;

Thomas Ehring, Remscheid, DE;

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/64 (2006.01); A61K 31/53 (2006.01); C07D 253/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Triazine derivatives of the formula (I) and physiologically acceptable salts and solvates thereof, in which R, R, A and Rare as defined in Claim, exhibit phosphodiesterase IV inhibition and can be employed for the treatment of allergic diseases, asthma, chronic bronchitis, atopic dermatitis, psoriasis and other skin diseases, inflammatory diseases, autoimmune diseases, such as, for example, rheumatoid arthritis, multiple sclerosis, Crohn's disease, diabetes mellitus or ulcerative colitis, osteoporosis, transplant rejection reactions, cachexia, tumour growth or tumour metastases, sepsis, memory disorders, atherosclerosis and AIDS, furthermore for inhibiting the formation of TNFα.


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