The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2009

Filed:

Aug. 01, 2003
Applicants:

Jonathan C. Makielski, Fitchburg, WI (US);

Bin YE, Madison, WI (US);

Michael J. Ackerman, Rochester, MN (US);

Inventors:

Jonathan C. Makielski, Fitchburg, WI (US);

Bin Ye, Madison, WI (US);

Michael J. Ackerman, Rochester, MN (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/12 (2006.01); C12N 5/10 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses four groups of SCN5A variants that represent the most common SCN5A variants in humans. A specific mutation in one of the variants has been shown to display a different phenotype in relation to a human heart disease than other variants and known human sodium channel α subunits with corresponding mutations. The present invention provides new tools to study mutations and to design or identify new diagnostic and treatment strategies or agents for sodium channel related diseases or conditions.


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