The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 03, 2009
Filed:
Feb. 27, 2004
Jason R. Fink, Eagan, MN (US);
Keith B. Gorden, Maplewood, MN (US);
Kevin S. Gorski, White Bear Lake, MN (US);
Shalley K. Gupta, Woodbury, MN (US);
Xiaohong Qiu, Rosemount, MN (US);
John P. Vasilakos, Woodbury, MN (US);
Jason R. Fink, Eagan, MN (US);
Keith B. Gorden, Maplewood, MN (US);
Kevin S. Gorski, White Bear Lake, MN (US);
Shalley K. Gupta, Woodbury, MN (US);
Xiaohong Qiu, Rosemount, MN (US);
John P. Vasilakos, Woodbury, MN (US);
3M Innovative Properties Company, St. Paul, MN (US);
Abstract
Methods of identifying a compound that selectively modulates at least one TLR-mediated cellular activity are disclosed. Generally, the methods include identifying a compound as a compound that selectively modulates at least one TLR-mediated cellular activity if the compound modulates one TLR-mediated cellular activity to a different extent than it modulates a second TLR-mediated cellular activity. Compounds so identified and pharmaceutical compositions including such compounds are also disclosed. Methods of selectively modulating immune cells and methods of treating certain conditions are also provided. Such methods include administering to cells or a subject a compound that selectively modulates a TLR-mediated cellular activity.