The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2009

Filed:

Jun. 03, 2003
Applicants:

Jianmin Fang, Foster City, CA (US);

Karin Jooss, San Francisco, CA (US);

Jing-jing Qian, Foster City, CA (US);

Inventors:

Jianmin Fang, Foster City, CA (US);

Karin Jooss, San Francisco, CA (US);

Jing-Jing Qian, Foster City, CA (US);

Assignee:

Cell Genesys, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/01 (2006.01); C12N 15/00 (2006.01); C12N 15/11 (2006.01); C12N 15/13 (2006.01); C12N 5/10 (2006.01); C12P 21/00 (2006.01); C12P 21/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

Single vector constructs for expression of a functional antibody molecule are described. The vectors have a self-processing cleavage site between two heterologous DNA coding sequences allowing for expression of two coding sequences using a single promoter. Exemplary vector constructs comprise a foot and mouth disease virus (FMDV) 2A sequence. The vector constructs can be used in methods relating to antibody delivery and therapy and in the production of a biologically active antibody or fragment thereof.


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