The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 2009
Filed:
Feb. 02, 2007
Gerald F. Sigler, Carmel, IN (US);
Raymond A. Hui, Indianapolis, IN (US);
Ina Deras, San Diego, CA (US);
Richard Terry Root, Fishers, IN (US);
Mitali Ghoshal, Noblesville, IN (US);
Erasmus Huber, Finning, DE;
Herbert W. Von Der Eltz, Weilheim, DE;
Sigrun Metz, Munich, DE;
Peter Kern, Penzberg, DE;
Gerald F. Sigler, Carmel, IN (US);
Raymond A. Hui, Indianapolis, IN (US);
Ina Deras, San Diego, CA (US);
Richard Terry Root, Fishers, IN (US);
Mitali Ghoshal, Noblesville, IN (US);
Erasmus Huber, Finning, DE;
Herbert W. Von Der Eltz, Weilheim, DE;
Sigrun Metz, Munich, DE;
Peter Kern, Penzberg, DE;
Roche Diagnostics Operations, Inc., Indianapolis, IN (US);
Abstract
Activated haptens useful for generating immunogens to HIV protease inhibitors, immunogens useful for producing antibodies to HIV protease inhibitors, and antibodies and labeled conjugates useful in immunoassays for the HIV protease inhibitor saquinavir. The novel haptens feature an activated functionality at the central, non-terminal hydroxyl group. Also described are monoclonal antibodies specific for saquinavir having less than 10% cross-reactivity with lopinavir, nelfinavir, amprenavir, ritonavir, and indinavir, and a murine hybridoma producing said antibodies.