The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 2009
Filed:
Dec. 19, 2006
Jean M. Gudas, Pacific Palisades, CA (US);
Mary Haak-frendscho, Newark, CA (US);
Orit Foord, Foster-City, CA (US);
Meina L. Liang, Danville, CA (US);
Kiran Ahluwalia, Fremont, CA (US);
Sunil Bhakta, Hayward, CA (US);
Jean M. Gudas, Pacific Palisades, CA (US);
Mary Haak-Frendscho, Newark, CA (US);
Orit Foord, Foster-City, CA (US);
Meina L. Liang, Danville, CA (US);
Kiran Ahluwalia, Fremont, CA (US);
Sunil Bhakta, Hayward, CA (US);
AstraZeneca AB, Sodertalje, SE;
Abstract
Embodiments of the invention described herein relate to antibodies directed to the antigen monocyte chemo-attractant protein-1 (MCP-1) and uses of such antibodies. In particular, in accordance with some embodiments, there are provided fully human monoclonal antibodies directed to the antigen MCP-1. Nucelotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.