The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 27, 2009

Filed:

Feb. 18, 2005
Applicants:

James C. Powers, Atlanta, GA (US);

Juliana Asgian, Fullerton, CA (US);

Özlem Dogan Ekici, Columbus, OH (US);

Marion Gabriele Gotz, Hirschau, DE;

Karen Ellis James, Cumming, GA (US);

Zhao Zhao LI, Norcross, GA (US);

Brian Rukamp, Greenleaf, WI (US);

Inventors:

James C. Powers, Atlanta, GA (US);

Juliana Asgian, Fullerton, CA (US);

Özlem Dogan Ekici, Columbus, OH (US);

Marion Gabriele Gotz, Hirschau, DE;

Karen Ellis James, Cumming, GA (US);

Zhao Zhao Li, Norcross, GA (US);

Brian Rukamp, Greenleaf, WI (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/15 (2006.01); C07C 243/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present disclosure provides compositions for inhibiting proteases, methods for synthesizing the compositions, and methods of using the disclosed protease inhibitors. Aspects of the disclosure include a peptidyl propenoyl hydrazide compositions that inhibit proteases, for example cysteine proteases, either in vivo or in vitro.


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