The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 2009
Filed:
Mar. 30, 2005
Applicants:
James E. Sheppeck, Wilmington, DE (US);
Jingwu Duan, Newark, DE (US);
Chu-biao Xue, Hockessin, DE (US);
Zelda Wasserman, Wilmington, DE (US);
Inventors:
James E. Sheppeck, Wilmington, DE (US);
Jingwu Duan, Newark, DE (US);
Chu-Biao Xue, Hockessin, DE (US);
Zelda Wasserman, Wilmington, DE (US);
Assignee:
Bristol-Myers Squibb Company, Princeton, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/00 (2006.01); C07D 233/00 (2006.01); C07D 221/00 (2006.01); C07D 215/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present application describes novel hydantoin derivatives of formula (I): or pharmaceutically acceptable salt or prodrug forms thereof, wherein A, B, R, R, R, R, R, R, R, R, and n are defined in the present specification, which are useful as inhibitors of matrix metalloproteinases (MMP), TNF-α converting enzyme (TACE), aggrecanase, or a combination thereof.