The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 27, 2009

Filed:

Jun. 17, 2005
Applicants:

Tesfaye Biftu, Freehold, NJ (US);

Danqing Feng, Branchburg, NJ (US);

Ying-duo Gao, Edison, NJ (US);

Suresh Singh, Kendall Park, NJ (US);

Ann E. Weber, Scotch Plains, NJ (US);

Inventors:

Tesfaye Biftu, Freehold, NJ (US);

Danqing Feng, Branchburg, NJ (US);

Ying-Duo Gao, Edison, NJ (US);

Suresh Singh, Kendall Park, NJ (US);

Ann E. Weber, Scotch Plains, NJ (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/00 (2006.01); A01N 43/58 (2006.01); A01N 43/60 (2006.01); A01N 43/90 (2006.01); A01N 43/38 (2006.01); A61K 31/00 (2006.01); A61K 31/50 (2006.01); A61K 31/495 (2006.01); A61K 31/519 (2006.01); A61K 31/40 (2006.01); C07D 243/00 (2006.01); C07D 471/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to novel substituted aminocyclohexanes which are inhibitors of the dipeptidyl peptidase-IV enzyme ('DPP-IV inhibitors') and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.


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