The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 2009
Filed:
Sep. 22, 2004
Applicants:
Trini Arroyo, Palo Alto, CA (US);
Yuanhao LI, Palo Alto, CA (US);
Inventors:
Trini Arroyo, Palo Alto, CA (US);
Yuanhao Li, Palo Alto, CA (US);
Assignee:
Cell Genesys, Inc., South San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/16 (2006.01); C12N 15/861 (2006.01);
U.S. Cl.
CPC ...
Abstract
Liver cancer, particularly hepatocellular carcinoma specific promoter sequences and adenovirus vehicles are provided. By providing for transcriptional initiating regulation dependent upon transcription factors that are only active in specific, limited cell types, virus replication will be restricted to the target cells. The modified adenovirus may be used as a vehicle for introducing new genetic capability, particularly associated with cytotoxicity, for treating neoplasia.