The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 2009
Filed:
Nov. 27, 2002
Rudolf Valenta, Theresienfeld, AT;
Susanne Vrtala, Vienna, AT;
Sabine Stummfoll, St. Peter, AT;
Hans Grönlund, Lidingö, SE;
Monika Grote, Münster, DE;
Luca Vangelista, Padua, IT;
Annalisa Pastore, London, GB;
Wolfgang R. Sperr, Vienna, AT;
Peter Valent, Vienna, AT;
Dietrich Kraft, Vienna, AT;
Rudolf Valenta, Theresienfeld, AT;
Susanne Vrtala, Vienna, AT;
Sabine Stummfoll, St. Peter, AT;
Hans Grönlund, Lidingö, SE;
Monika Grote, Münster, DE;
Luca Vangelista, Padua, IT;
Annalisa Pastore, London, GB;
Wolfgang R. Sperr, Vienna, AT;
Peter Valent, Vienna, AT;
Dietrich Kraft, Vienna, AT;
Phadia AB, Uppsala, SE;
Abstract
The invention relates to a hypoallergenic immunogenic molecule derived from the Phl p 6 allergen, wherein the Phl p 6 molecule has an N-terminal and/or C-terminal deletion which makes the molecule at least substantially lack IgE binding capacity. The invention also relates to a hypoallergenic immunogenic combination of molecules derived from the Phl p 6 allergen, comprising (i) a Phl p 6 molecule having an N-terminal deletion which makes the molecule at least substantially lack IgE binding capacity, and (ii) a Phl p 6 molecule having a C-terminal deletion which makes the molecule at least substantially lack IgE binding capacity, which two molecules together encompass the complete sequence of Phl p 6. The invention further relates to the use of the hypoallergenic immunogenic molecule or molecule mixture in hyposensitization and diagnosis.