The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 13, 2009

Filed:

Jul. 25, 2003
Applicants:

Maria Tang, Fairfield, CA (US);

Alan Sloma, Davis, CA (US);

David Sternberg, Davis, CA (US);

Regine Behr, Roseville, CA (US);

Inventors:

Maria Tang, Fairfield, CA (US);

Alan Sloma, Davis, CA (US);

David Sternberg, Davis, CA (US);

Regine Behr, Roseville, CA (US);

Assignee:

Novozymes, Inc., Davis, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to methods of producing a heterologous biological substance, comprising: (a) cultivating a mutant of a parentcell under conditions conducive for the production of the heterologous biological substance, wherein (i) the mutant cell comprises a first nucleic acid sequence directing synthesis of the heterologous biological substance and a second nucleic acid sequence comprising a modification of at least one of the genes cypX and yvmC, which are involved in the production of a red pigment, and (ii) the mutant cell is deficient in the production of the red pigment compared to the parentcell when cultivated under the same conditions; and (b) recovering the heterologous biological substance from the cultivation medium. The present invention also relates to mutants ofcells and methods for producing the mutants.


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