The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 13, 2009

Filed:

Sep. 13, 2002
Applicants:

Robert L. Sah, San Diego, CA (US);

Kelvin W. LI, San Diego, CA (US);

Travis J. Klein, San Diego, CA (US);

Barbara L. Schumacher, Cardiff by the Sea, CA (US);

Koichi Masuda, Wilmette, IL (US);

Eugene J-m. A. Thonar, Lockport, IL (US);

Inventors:

Robert L. Sah, San Diego, CA (US);

Kelvin W. Li, San Diego, CA (US);

Travis J. Klein, San Diego, CA (US);

Barbara L. Schumacher, Cardiff by the Sea, CA (US);

Koichi Masuda, Wilmette, IL (US);

Eugene J-M. A. Thonar, Lockport, IL (US);

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61F 2/28 (2006.01); A61F 2/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to a cultured, stratified cartilage tissue that comprises a tissue-engineered, cohesive cartilage construct comprised of two or more cartilage layers, wherein each cartilage layer comprises chondrogenic cells having a chondrocytic phenotype corresponding to chondrocytes present in: a superficial-tangential zone of natural cartilage; a middle-transitional zone of natural cartilage; a deep-radial zone of natural cartilage; or a calcified cartilage zone of natural cartilage.


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