The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2009
Filed:
Dec. 30, 2004
Alain R. E. Carre, Le Chatelet-En-Brie, FR;
Alexander M. Efremov, St. Petersburg, RU;
YE Fang, Painted Post, NY (US);
Yulong Hong, Painted Post, NY (US);
Valerie Lacarriere, Larchant, FR;
Joydeep Lahiri, Painted Post, NY (US);
Fang Lai, Painted Post, NY (US);
John C. Mauro, Painted Post, NY (US);
Srikanth Raghavan, Ithaca, NY (US);
Brian L. Webb, Painted Post, NY (US);
Alain R. E. Carre, Le Chatelet-En-Brie, FR;
Alexander M. Efremov, St. Petersburg, RU;
Ye Fang, Painted Post, NY (US);
Yulong Hong, Painted Post, NY (US);
Valerie Lacarriere, Larchant, FR;
Joydeep Lahiri, Painted Post, NY (US);
Fang Lai, Painted Post, NY (US);
John C. Mauro, Painted Post, NY (US);
Srikanth Raghavan, Ithaca, NY (US);
Brian L. Webb, Painted Post, NY (US);
Corning Incorporated, Corning, NY (US);
Abstract
The invention relates to G protein-coupled receptor (GPCR) microarrays on porous substrates for structural or functional analyses of GPCRs, and methods of preparing porous substrate surfaces for receiving membranes that comprise GPCRs. In one embodiment, a GPCR microarray of the invention comprises a membrane adhered to an upper surface of a porous substrate, the membrane spanning across a plurality of pores on the porous substrate to form a plurality of cavities having sufficient geometry to permit entry of assay reagents into each cavity, thereby allowing access of assay reagents to both sides of GPCR in the membrane.