The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 2009

Filed:

Mar. 15, 2004
Applicants:

Yeon-soo Kim, Seoul, KR;

IN Seop SO, Daejeon, KR;

Young-kwan Lee, Daejeon, KR;

Jongpil Kim, Daejeon, KR;

Moonkyung Kang, Daejeon, KR;

Hyojeong Hong, Daejeon, KR;

Inventors:

Yeon-Soo Kim, Seoul, KR;

In Seop So, Daejeon, KR;

Young-Kwan Lee, Daejeon, KR;

Jongpil Kim, Daejeon, KR;

Moonkyung Kang, Daejeon, KR;

Hyojeong Hong, Daejeon, KR;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/12 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
Abstract

The inventive chimeric ligand in the form of a fusion polypeptide of a single-chain antibody specific for Tag-72 surface antigen and GaLV envelope glycoprotein shows high transduction efficiency to cancer cells, specifically infects target cells and efficiently delivers a therapeutic gene. Accordingly, the inventive chimeric ligand can be effectively used for gene therapy to inhibit tumor growth and metastasis.


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