The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 2009

Filed:

Mar. 07, 2003
Applicants:

Masayuki Kawakami, Minami-ashigara, JP;

Hiroshi Kitaguchi, Minami-ashigara, JP;

Kai Licha, Falkensee, DE;

Christin Perlitz, Berlin, DE;

Hiroaki Eguchi, Kawanishi, JP;

Natsuko Tsuda, Nishinomiya, JP;

Kazuhiro Aikawa, Minami-ashigara, JP;

Inventors:

Masayuki Kawakami, Minami-ashigara, JP;

Hiroshi Kitaguchi, Minami-ashigara, JP;

Kai Licha, Falkensee, DE;

Christin Perlitz, Berlin, DE;

Hiroaki Eguchi, Kawanishi, JP;

Natsuko Tsuda, Nishinomiya, JP;

Kazuhiro Aikawa, Minami-ashigara, JP;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

A near infrared fluorescent contrast agent which is excellent in permeability in a living tissue and enables specific imaging of tumor and/or blood vessel, comprising a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, wherein R, R, R, and Rrepresent a C-Calkyl group or the like; R, R, R, R, R, R, R, and Rrepresent a hydrogen atom, a C-Calkyl group, an aryl group or the like; Xand Xrepresent a C-Calkyl group or an aryl group and Xand Xin total have 0 to 4 carboxyl groups; m, m, and mrepresents 0 or 1; Lto Lindependently represent a methine group; M represents a hydrogen atom, a metal, or a quaternary ammonium salt; and n represents an integer of 1 to 7 necessary for neutralizing charge.


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