The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2008
Filed:
Aug. 26, 2005
Michel Joseph Maurice André Guillaume, Berg, BE;
Yolande Lydia Lang, Vosselaar, BE;
Armin Roessler, Tengen, CH;
Lars Ulmer, Neuhausen, CH;
Stefan Marcel Herman Leurs, Vosselaar, BE;
Dirk DE Smaele, Wetteren, BE;
Michel Joseph Maurice André Guillaume, Berg, BE;
Yolande Lydia Lang, Vosselaar, BE;
Armin Roessler, Tengen, CH;
Lars Ulmer, Neuhausen, CH;
Stefan Marcel Herman Leurs, Vosselaar, BE;
Dirk De Smaele, Wetteren, BE;
Janssen Pharmaceutica N.V., Beerse, BE;
Abstract
The present invention relates to a novel process for the production of [2-(4-fluoro-benzyl)-phenyl]-acetic acid, a compound obtainable from phthalic anhydride. The process comprises the subsequent steps a) through e): In an alternative embodiment, the step e) is replaced by the steps f1) and f2): The present invention provides a process for the production of [2-(4-fluoro-benzyl)-phenyl]-acetic acid which is suitable for industrial scale reactors (e.g. which is cleaner and more efficient). Also, [2-(4-fluoro-benzyl)-phenyl]-acetic acid is obtained as a crystalline material with a purity >95%.