The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2008
Filed:
Jun. 25, 2002
Clive Leslie Branch, Harlow, GB;
Wai Ngor Chan, Harlow, GB;
Amanda Johns, Harlow, GB;
Christopher Norbert Johnson, Harlow, GB;
David John Nash, Harlow, GB;
Riccardo Novelli, Harlow, GB;
Jean-pierre Pilleux, Mayenne, FR;
Roderick Alan Porter, Harlow, GB;
Rachel Elizabeth Anne Stead, Harlow, GB;
Geoffrey Stemp, Harlow, GB;
Clive Leslie Branch, Harlow, GB;
Wai Ngor Chan, Harlow, GB;
Amanda Johns, Harlow, GB;
Christopher Norbert Johnson, Harlow, GB;
David John Nash, Harlow, GB;
Riccardo Novelli, Harlow, GB;
Jean-Pierre Pilleux, Mayenne, FR;
Roderick Alan Porter, Harlow, GB;
Rachel Elizabeth Anne Stead, Harlow, GB;
Geoffrey Stemp, Harlow, GB;
SmithKline Beecham p.l.c., Brentford, Middlesex, GB;
Abstract
This invention relates to N-aroyl cyclic amine derivatives of formula (I), wherein X represents a bond, oxygen, NRor a group (CH), wherein n represents 1, 2 or 3; Y represents CH, CO, CH(OH), or CHCH(OH); Het is an optionally substituted bicyclic heteroaryl group containing up to 4 heteroatoms selected from N, O and S; Arrepresents an optionally substituted phenyl or a 5- or 6-membered heterocyclyl group containing up to 3 heteroatoms selected from N, O and S and their use as pharmaceuticals, specifically as orexin receptor antagonists.