The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2008
Filed:
Jul. 20, 2005
Applicants:
Theresa O'keefe, Waltham, MA (US);
Peter Luciano, Maynard, MA (US);
Shixin Qin, Lexington, MA (US);
Inventors:
Assignee:
Critical Therapeutics, Inc., Lexington, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); A61K 39/00 (2006.01); C07H 21/04 (2006.01); C12P 21/04 (2006.01); C12N 5/00 (2006.01); C12N 5/16 (2006.01); C12N 15/64 (2006.01); C12N 1/20 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention is drawn to fusion proteins comprising a Receptor for Advanced Glycation Endproducts (RAGE) and an immunoglobulin element. The invention also encompasses methods of treating a condition characterized by activation of an inflammatory cytokine cascade comprising administering such fusion proteins. The invention is also drawn to nucleic acids encoding the fusion proteins, as well as vectors and cells comprising such nucleic acids.