The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2008
Filed:
Feb. 07, 2003
Andrew I. Damokosh, West Hartford, CT (US);
Natalia Iartchouk, Wayland, MA (US);
James J. Stec, Ii, Plymouth, MA (US);
Edwin A. Clark, Pennington, NJ (US);
Karen LU, Houston, TX (US);
Lynn Hartmann, Rochester, MN (US);
Robert C. Bast, Jr., Houston, TX (US);
Gordon B. Mills, Houston, TX (US);
Andrew I. Damokosh, West Hartford, CT (US);
Natalia Iartchouk, Wayland, MA (US);
James J. Stec, II, Plymouth, MA (US);
Edwin A. Clark, Pennington, NJ (US);
Karen Lu, Houston, TX (US);
Lynn Hartmann, Rochester, MN (US);
Robert C. Bast, Jr., Houston, TX (US);
Gordon B. Mills, Houston, TX (US);
Millennium Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
The present invention is directed to the identification of markers that can be used to determine whether ovarian cancer is sensitive or resistant to a therapeutic agent. In particular, the present invention is directed to the use of certain combinations of markers, wherein the expression of the markers correlates with sensitivity or resistance to a therapeutic agent. Thus, by examining the expression of the individual markers of a marker set, also referred to as the expression profile of the marker set, it is possible to determine whether a therapeutic agent, or combination of agents, will be most likely to reduce the growth rate of the ovarian cancer.