The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2008

Filed:

Sep. 24, 2004
Applicants:

Robert J. Devita, Westfield, NJ (US);

Peter Lin, Edison, NJ (US);

Sander G. Mills, Scotch Plains, NJ (US);

Jonathan R. Young, Southborough, MA (US);

Inventors:

Robert J. DeVita, Westfield, NJ (US);

Peter Lin, Edison, NJ (US);

Sander G. Mills, Scotch Plains, NJ (US);

Jonathan R. Young, Southborough, MA (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 239/00 (2006.01); C07D 213/04 (2006.01); C07D 207/00 (2006.01); C07D 233/00 (2006.01); C07D 333/02 (2006.01); C07D 321/00 (2006.01); C07D 307/00 (2006.01); A01N 43/58 (2006.01); A01N 43/64 (2006.01); A61K 31/41 (2006.01); A61K 31/38 (2006.01); A61K 31/335 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to certain phenyl pyrrolidine ether compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including emesis, depression, and anxiety.


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