The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2008

Filed:

Jun. 19, 2007
Applicants:

Frank X. H. Wu, Shrewsbury, MA (US);

Yat Sun OR, Watertown, MA (US);

Inventors:

Frank X. H. Wu, Shrewsbury, MA (US);

Yat Sun Or, Watertown, MA (US);

Assignee:

Enanta Pharmaceuticals, Inc., Watertown, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a cyclosporin analog of the following formula (I) or a pro-drug or pharmaceutically acceptable salt thereof: whereinA is of the formula: where Q, W, X, Y, and Z are defined herein. In a second embodiment, the present invention relates to pharmaceutical compositions comprising pro-drugs or pharmaceutically acceptable salts of the compounds of the present invention and the use thereof for treating autoimmune diseases or for the prevention of organ transplantation rejection in a subject. In a third embodiment, the present invention relates to processes for the production of novel cyclosporin analogs of the present invention.


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