The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 23, 2008
Filed:
Dec. 13, 2004
Jayasree Vasudevan, Anaheim, CA (US);
Rong Yang, Viejo, CA (US);
Liming Wang, Irvine, CA (US);
Xiaoxia Liu, Nashua, NH (US);
Kwok-yin Tsang, Irvine, CA (US);
Ling LI, Irvine, CA (US);
Janet Takeuchi, Anaheim, CA (US);
Thong VU, Garden Grove, CA (US);
Richard Beard, Newport Beach, CA (US);
Smita Bhat, Irvine, CA (US);
Roshantha A. Chandraratna, Laguna Hills, CA (US);
Jayasree Vasudevan, Anaheim, CA (US);
Rong Yang, Viejo, CA (US);
Liming Wang, Irvine, CA (US);
Xiaoxia Liu, Nashua, NH (US);
Kwok-Yin Tsang, Irvine, CA (US);
Ling Li, Irvine, CA (US);
Janet Takeuchi, Anaheim, CA (US);
Thong Vu, Garden Grove, CA (US);
Richard Beard, Newport Beach, CA (US);
Smita Bhat, Irvine, CA (US);
Roshantha A. Chandraratna, Laguna Hills, CA (US);
Allergan, Inc., Irvine, CA (US);
Abstract
The invention provides methods for treating an individual having a retinoid responsive disorder. In one embodiment, a method involves administering to the individual an effective amount of a selective CYP26B inhibitor, the selective CYP26B inhibitor having at least 10-fold selectivity for CYP26B relative to CYP26A. In another embodiment, a method involves administering to the individual an effective amount of a selective CYP26A inhibitor, the selective CYP26A inhibitor having a chemical formula set forth in the specification. The invention further provides screening methods for identifying a selective CYP26A inhibitor or selective CYP26B inhibitor.