The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 23, 2008
Filed:
Feb. 11, 2004
Cristopher John Wraight, Blackburn, AU;
George Arthur Werther, Camberwell, AU;
Nicholas M. Dean, Carlsbad, CA (US);
Kenneth W. Dobie, Carlsbad, CA (US);
Cristopher John Wraight, Blackburn, AU;
George Arthur Werther, Camberwell, AU;
Nicholas M. Dean, Carlsbad, CA (US);
Kenneth W. Dobie, Carlsbad, CA (US);
Antisense Therapeutics Ltd., Toorak, Victoria, AU;
Abstract
The present invention provides compositions and methods for modulating the expression of growth factor gene. In particular, this invention relates to compounds, particularly oligonucleotide compounds, which, in preferred embodiments, hybridize with nucleic acid molecules encoding the Insulin Like Growth Factor I receptor (IGF-I receptor or IGF-IR) and in particular human IGF-IR. Such compounds are exemplified herein to modulate proliferation which is relevant to the treatment of proliferative and inflammatory skin disorders and cancer. It will be understood, however, that the compounds can be used for any other condition in which the IGF-IR is involved including inflammatory conditions.