The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2008

Filed:

Jul. 22, 2003
Applicants:

Shuichi Mizuno, Brookline, MA (US);

Akihiko Kusanagi, Brookline, MA (US);

Laurence J. B. Tarrant, Easthampton, MA (US);

Toshimasa Tokuno, Tokyo, JP;

Robert Lane Smith, Palo Alto, CA (US);

Inventors:

Shuichi Mizuno, Brookline, MA (US);

Akihiko Kusanagi, Brookline, MA (US);

Laurence J. B. Tarrant, Easthampton, MA (US);

Toshimasa Tokuno, Tokyo, JP;

Robert Lane Smith, Palo Alto, CA (US);

Assignee:

Histogenics Corporation, Waltham, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/00 (2006.01); C12N 11/02 (2006.01); C12N 11/08 (2006.01); C12N 5/06 (2006.01); C12N 5/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for treatment of injured, damaged, diseased or aged articular cartilage using neo-cartilage constructs implanted into a joint cartilage lesion in situ. The implantation of the construct initiates and achieves incorporation of neo-cartilage into a native surrounding cartilage including a formation of a new superficial cartilage layer overgrowing and sealing the lesion in the joint cartilage.


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