The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2008

Filed:

May. 17, 2006
Applicants:

Jonathan Houze, San Mateo, CA (US);

Jiwen Liu, Foster City, CA (US);

Zhihua MA, San Mateo, CA (US);

Julio C. Medina, San Carlos, CA (US);

Michael J. Schmitt, San Francisco, CA (US);

Rajiv Sharma, Fremont, CA (US);

Ying Sun, Albany, CA (US);

Yingcai Wang, Fremont, CA (US);

Liusheng Zhu, Burlingame, CA (US);

Inventors:

Jonathan Houze, San Mateo, CA (US);

Jiwen Liu, Foster City, CA (US);

Zhihua Ma, San Mateo, CA (US);

Julio C. Medina, San Carlos, CA (US);

Michael J. Schmitt, San Francisco, CA (US);

Rajiv Sharma, Fremont, CA (US);

Ying Sun, Albany, CA (US);

Yingcai Wang, Fremont, CA (US);

Liusheng Zhu, Burlingame, CA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 263/32 (2006.01); C07D 257/04 (2006.01); C07D 249/04 (2006.01); C07D 249/08 (2006.01); C07D 277/22 (2006.01); C07D 277/24 (2006.01); C07C 59/13 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds useful, for example, for modulating insulin levels in a subject, having the general formula I: wherein Q is an optionally substituted phenyl; L is a bond or O; P is a benzene or an optionally substituted thiazole ring; and Rhas the values provided herein. The present invention also provides compositions, uses, and methods for use of the compounds, for instance, for treatment of type II diabetes.


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