The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2008

Filed:

Oct. 09, 2001
Applicants:

Herman Waldmann, Oxford, GB;

Mark Raymond Frewin, Oxford, GB;

Lisa Kim Gilliland, Midlothian, GB;

Luis Richardo Simoes Da Silva Graca, Oxford, GB;

Inventors:

Herman Waldmann, Oxford, GB;

Mark Raymond Frewin, Oxford, GB;

Lisa Kim Gilliland, Midlothian, GB;

Luis Richardo Simoes da Silva Graca, Oxford, GB;

Assignee:

ISIS INNOVATION, Inc., Oxford, GB;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C60K 14/00 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract

A pharmaceutical comprising a therapeutic protein that binds to a therapeutic target, the protein being modified with a compound that inhibits binding of the protein to the therapeutic target, the modified protein being effective for reducing an immune response against the protein and for producing a therapeutic effect by binding to the therapeutic target. The therapeutic protein may be an antibody that includes an antibody combining site that binds to the therapeutic target.


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