The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7465750 B1

PDF
Full Text
Expired
Date of Patent:
Dec. 16, 2008

Filed:

Sep. 06, 2006
Applicants:

Thomas P. Blackburn, Hoboken, NJ (US);

Michael J. Konkel, Garfield, NJ (US);

Lakmal W. Boteju, Cedar, NJ (US);

Ian Jamie Talisman, New York, NY (US);

John M. Wetzel, Fairlawn, NJ (US);

Mathivanan Packiarajan, Saddle Brook, NJ (US);

Heidi Chen, Wyckoff, NJ (US);

Hermo Jimenez, Hackensack, NJ (US);

Inventors:

Thomas P. Blackburn, Hoboken, NJ (US);

Michael J. Konkel, Garfield, NJ (US);

Lakmal W. Boteju, Cedar, NJ (US);

Ian Jamie Talisman, New York, NY (US);

John M. Wetzel, Fairlawn, NJ (US);

Mathivanan Packiarajan, Saddle Brook, NJ (US);

Heidi Chen, Wyckoff, NJ (US);

Hermo Jimenez, Hackensack, NJ (US);

Assignee:

H. Lundbeck A/S, Paramus, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/34 (2006.01); A61K 31/381 (2006.01); C07D 403/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention is directed to pyrimidine and indolone derivatives which are selective antagonists for the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety. This invention also provides a method of treating depression and/or anxiety in a subject which comprises administering to the subject a composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of a GAL3 receptor antagonist.


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Blackburn, Thomas. (2008). Use of gal3 antagonist for treatment of depression and/or anxiety and compounds useful in such methods (U.S. Patent No. 7465750). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7465750

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