The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2008

Filed:

Jun. 06, 2007
Applicants:

Ying Wang, Beijing, CN;

Yingmei Zhang, Beijing, CN;

Wenling Han, Beijing, CN;

Dalong MA, Beijing, CN;

Yanan Liu, Beijing, CN;

Caihua Yin, Beijing, CN;

Linjie Tian, Beijing, CN;

Dan LI, Beijing, CN;

Inventors:

Ying Wang, Beijing, CN;

Yingmei Zhang, Beijing, CN;

Wenling Han, Beijing, CN;

Dalong Ma, Beijing, CN;

Yanan Liu, Beijing, CN;

Caihua Yin, Beijing, CN;

Linjie Tian, Beijing, CN;

Dan Li, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/10 (2006.01); A61K 38/16 (2006.01); C07K 14/435 (2006.01); C07K 7/08 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Polypeptides having an amino acid sequence of SEQ ID NO: 2, and having amino acid residues 9 to 27 of SEQ ID NO: 2 are disclosed, which are together named C-terminal polypeptides of CKLF1. Also disclosed is a pharmaceutical composition containing a therapeutically effective amount of the CKLF1 C-terminal polypeptide and pharmaceutically acceptable salts, carrier or excipient. Further disclosed are the polynucleotides encoding the C-terminal polypeptides of CKLF1, and vectors and host cells containing the polynucleotides; the in vitro assays for detecting the expression level of the polypeptide or polynucleotide in a test sample; and the monoclonal or polyclonal antibodies against the polypeptides or active fragments thereof. The polypeptides of the present invention can be pharmaceutically used for treating the HIV infection, allergic disease, allograft rejection, diseases in brain and autoimmune diseases.


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