The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2008
Filed:
Dec. 10, 2003
Applicants:
Jeanine D. Mattson, San Francisco, CA (US);
Terrill Mcclanahan, Sunnyvale, CA (US);
Inventors:
Jeanine D. Mattson, San Francisco, CA (US);
Terrill McClanahan, Sunnyvale, CA (US);
Assignee:
Schering-Plough Animal Health Corporation, Summit, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/51 (2006.01); C07K 14/00 (2006.01); C12N 5/00 (2006.01); C12N 15/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides isolated nucleic acid molecules that encode a substantial part of canine RANKL polypeptide, including the extracellular domains of that polypeptide, the polypeptide and fragments thereof. Vectors and host cells encoding and expressing canine RANKL polypeptide are provided, as well as antibodies that bind to RANKL and that inhibit RANKL activity. Also provided are methods of treating an animal to inhibit or treat the loss of bone minerals.