The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2008
Filed:
Feb. 01, 2002
Applicants:
Nilgun E. Tumer, Belle Mead, NJ (US);
Katalin A. Hudak, Toronto, CA;
Bijal Parikh, Union, NJ (US);
Inventors:
Assignee:
Rutgers, The State University, New Brunswick, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 36/00 (2006.01); C07K 14/415 (2006.01);
U.S. Cl.
CPC ...
Abstract
Disclosed are PAP mutants that are less toxic than wild type PAP and that exhibit depurination activity. Also disclosed are transgenic plants that procedure the PAP mutants, and methods for preparing the plants. Further disclosed are bioconjugates containing the PAP mutants, pharmaceutical compositions containing the bioconjugates, and methods of administering the compositions to treat disease.