The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 09, 2008

Filed:

Apr. 05, 2007
Applicants:

Thierry Gallet, Palaiseau, FR;

Patrick Lardenois, Bourg-la-Reine, FR;

Alistair Lochead, Charenton le Pont, FR;

Severine Marguerie, Rennes, FR;

Alain Nedelec, Colombes, FR;

Mourad Saady, Paris, FR;

Franck Slowinski, Thieux, FR;

Philippe Yaiche, Les Lilas, FR;

Inventors:

Thierry Gallet, Palaiseau, FR;

Patrick Lardenois, Bourg-la-Reine, FR;

Alistair Lochead, Charenton le Pont, FR;

Severine Marguerie, Rennes, FR;

Alain Nedelec, Colombes, FR;

Mourad Saady, Paris, FR;

Franck Slowinski, Thieux, FR;

Philippe Yaiche, Les Lilas, FR;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 25/28 (2006.01); A61K 31/55 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to an use of pyrimidone derivative represented by formula (I) or a salt thereof: wherein m, n, p, X, Y, R1, R2, R3, R4 and R5 are as defined herein for treating a variety of disease states. More specifically, the invention relates to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3β or GSK3β and cdk5/p25, such as Alzheimer's disease.


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