The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 09, 2008

Filed:

May. 25, 2006
Applicants:

Susan E. Conroy, London, GB;

Heidrun Engler, San Diego, CA (US);

Daniel C. Maneval, San Diego, CA (US);

Inventors:

Susan E. Conroy, London, GB;

Heidrun Engler, San Diego, CA (US);

Daniel C. Maneval, San Diego, CA (US);

Assignees:

Canji, Inc., Palo Alto, CA (US);

Innovata Limited, Ruddington, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/861 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides formulations and methods to enhance the delivery of nucleic acids to cells. Formulations comprising dextrin polymers in combination with sugars provide enhanced delivery of nucleic acids, particularly eucaryotic expression vectors, demonstrate enhanced delivery of nucleic acids to cells in vivo. The present invention also provides methods of treatment in combination with such formulations.


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